Basic carb tuning, set to the factory set point (if available*) 1.5 ish turns out if generally close enough. Set the idle screw open a bit. The key is to just get it to run at this point. Get it running and let it get some heat in it. Set the low screw. Turn in till the rpm rises abruptly then out till it bogs a bit. Somewhere near the middle will be about right to start. Some fiddling with the idle screw may be nessisary to keep idle rpm. At this point start driving around snapping the throttle. No bog, good acceleration is what you're after. Typically a slightly rich setting is where you'll end up. It's OK to adjust the idle screw/low screw to maintain idle rpm. Then start your wot pulls and adjust the high needle. There's about ~30% overlap in the needles, so you may have to go back and readjust the low needle to find the sweet spot.
This can be quite daunting if you're new to 2 strokes but you'll get it eventually. Just remember slightly rich settings won't blow an engine but lean will kill an engine fast.